Dr Geoffrey Fairris DM FRCP(Consultant in Surgical Laser & Cosmetic Dermatology)
Bowen's Disease is caused by the cumulative effect of ultraviolet light upon the DNA in skin cells.
Bowen's disease is a pre-cancer. The abnormal cells are confined to the outer layer of the skin. While the cells remain in the outer layer of the skin, the disease will not spread to other parts of the body.
Over a ten-year period, 10-20% of areas of Bowen's disease will turn into a squamous cell carcinoma. If this happens, the area thickens, ulcerates or starts to bleed or weep regularly. At this stage, it must be treated.
Surgery is the gold standard treatment. Photodynamic therapy leaves a better cosmetic result and is a better treatment when the skin is thin and delicate.
Efudix cream, cryotherapy and Aldara cream can be most practical than photodynamic therapy but the side-effects of these treatments are more severe and last longer.
Wearing a sunscreen may help. 3ml of sunscreen with SPF 20 and *** to **** UVA protection should be applied to each lower leg every morning. Sunscreens containing mexoryl are amongst the least white available.